LIVIA — PPI Network

Need the input? Generate it with lis.py from AFM-LIS.

① lis.py CSV output *

Drop CSV files (or click)

iLIS read directly · CSV, .zip, .xlsx (+ FASTA for the cLIP hand-off) · all-by-all → rich network

▶ Try example — fly small interactome · 565 proteins in the file; those with no pair past the cutoff are left out of the network (from Kim et al. 2026)

② Identity map optional

Relabel nodes to your names

name,chain,<id cols> · e.g. uniprot, gene

Names showing as IDs (UniProt accession, FlyBase, Entrez) instead of gene symbols? ✨ Auto-convert names → gene symbols — via mygene.info + UniProt. on load

Names not resolving to gene symbols? Fill in the identity-map template above, or use auto-convert and pick the right species — FBpp / FBgn, UniProt accessions and Entrez IDs all resolve. Still stuck? Open an issue on GitHub.

③ Node subset optional

Rebuild with only these

one node per row · re-runs Leiden

↓ current nodes template ·

④ Cluster map optional

Use your own clusters

node,cluster per row · overrides Leiden · unlisted nodes dropped

↓ current nodes template ·

No files loaded.

iLIS ≥ resolution objective seed

Modules

Build a network to see communities.

LIVIA — PPI Network Builder beta

Modules

LIVIA — PPI Network Builder ^beta